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ID: ALA1137691
Journal: Eur J Med Chem
Title: Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity.
Authors: Balan AM, Florea O, Moldoveanu C, Zbancioc G, Iurea D, Mangalagiu II.
Abstract: Herein we report a feasible study concerning syntheses, structure and antimicrobial activity of some new diazinium salts with dihydroxyacetophenone skeleton. A fast, general, environmentally friendly, and facile method for preparation of diazinium salts under microwave and ultrasounds irradiation is presented. Antimicrobial tests prove that some diazine compounds have a remarkable activity against different microorganisms (germs and fungi), the pyrimidine derivatives being more active. Correlations between structure and antimicrobial activity are reported.
CiteXplore: 18672317