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ID: ALA1137711

Journal: Eur J Med Chem

Title: Design, synthesis, structure-activity relationship and antibacterial activity series of novel imidazo fused quinolone carboxamides.

Authors: Reddy GV, Kanth SR, Maitraie D, Narsaiah B, Rao PS, Kishore KH, Murthy US, Ravi B, Kumar BA, Parthasarathy T.

Abstract: A series of novel 7,8 and 1,8 imidazo fused quinolone carboxamides are synthesized and evaluated against antibacterial activity. 1,8 Imidazo fused quinolones exhibit moderate antibacterial activity. Molecular modeling studies were carried out to optimize the pharmacophore.

CiteXplore: 18775585

DOI: 10.1016/j.ejmech.2008.07.024