Dammarane-type Saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cells.

ID: ALA1137810

Journal: J Nat Prod

Title: Dammarane-type Saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cells.

Authors: Zou K, Zhu S, Meselhy MR, Tohda C, Cai S, Komatsu K.

Abstract: Four new dammarane-type saponins (1-4), named yesanchinosides G-J, together with nine ginsenosides (5-13) were isolated from Ye-Sanchi, the underground part of Panax japonicus collected in the south of Yunnan Province, China. Their structures were elucidated on the basis of spectroscopic and chemical methods. Ginsenosides Rb(1) and Rb(3) and notoginsenosides R(4) (6) and Fa (7) showed significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.

CiteXplore: 12350149

DOI: 10.1021/np0201117

Patent ID: ┄