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ID: ALA1137916
Journal: Bioorg Med Chem Lett
Title: 5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa.
Authors: Batt DG, Qiao JX, Modi DP, Houghton GC, Pierson DA, Rossi KA, Luettgen JM, Knabb RM, Jadhav PK, Wexler RR.
Abstract: Structural features of a 5-amidinoindole inhibitor of factor Xa, which displayed modest inhibition of factor IXa were varied to increase potency and improve selectivity for factor IXa.
CiteXplore: 15454209