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ID: ALA1137951
Journal: Bioorg Med Chem Lett
Title: Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones.
Authors: Lee H, Cho S, Namgoong K, Jung JK, Cho J, Yang SI.
Abstract: A series of benzo[g]quinoxaline-5,10-dione derivatives carrying a 7-dialkylaminomethyl substituent was synthesized and their in vitro cytotoxic activities were evaluated against four human cancer cell lines (HCT-15, SK-OV-3, MD-MB-468 and T-47D). The most active compound 9d showed cytotoxic activity comparable to that of doxorubicin against HCT-15 cancer cell line.
CiteXplore: 14980672