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ID: ALA1138121
Journal: Bioorg Med Chem Lett
Title: Pentacyclic triterpenes. Part 2: Synthesis and biological evaluation of maslinic acid derivatives as glycogen phosphorylase inhibitors.
Authors: Wen X, Zhang P, Liu J, Zhang L, Wu X, Ni P, Sun H.
Abstract: The synthesis of a series of maslinic acid derivatives is described and their effect on rabbit muscle glycogen phosphorylase a evaluated. Within this series of compounds, 15 (IC(50)=7 microM) is the most potent GPa inhibitor. SAR of the maslinic acid derivatives are discussed.
CiteXplore: 16246555