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ID: ALA1138385
Journal: Bioorg Med Chem Lett
Title: Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor.
Authors: Danilova O, Li B, Szardenings AK, Huber BT, Rosenblum JS.
Abstract: A cell permeable DPP II [also known as DPP2, DPP7, and quiescent cell proline dipeptidase (QPP)] inhibitor has been synthesized. The azabicyclo[3.3.0]octane-based inhibitor is potent and selective and elicits very similar quiescent lymphocyte death to previously characterized inhibitors that are not as selective.
CiteXplore: 17055271