Document Report Card
Basic Information
ID: ALA1139035
Journal: Bioorg Med Chem Lett
Title: Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power.
Authors: Ferreira IC, Queiroz MJ, Vilas-Boas M, Estevinho LM, Begouin A, Kirsch G.
Abstract: The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure-activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO(2)Et, CO(2)H).
CiteXplore: 16325403