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ID: ALA1139036

Journal: Bioorg Med Chem Lett

Title: Sarcosine based indandione hGlyT1 inhibitors.

Authors: Thomson CG, Duncan K, Fletcher SR, Huscroft IT, Pillai G, Raubo P, Smith AJ, Stead D.

Abstract: A series of sarcosine based indandione hGlyT1 inhibitors has been developed. Optimization of substitution around the indandione and sarcosine moieties has led to highly potent inhibitors at hGlyT1, which show selectivity over a number of other receptors.

CiteXplore: 16321523

DOI: 10.1016/j.bmcl.2005.11.041