Basic Information
ID: ALA1139119
Journal: Bioorg Med Chem Lett
Title: Anti-mycobacterial activity of a bis-sulfonamide.
Authors: Wilkinson BL, Bornaghi LF, Wright AD, Houston TA, Poulsen SA.
Abstract: A bis-arylsulfonamide, 7, has been identified that exhibits growth inhibition of Mycobacterium smegmatis at less than 25 microg/mL, but has no such activity against Escherichia coli or Staphylococcus aureus. A closely related bis-arylsulfonamide (8) was much less active, but was the only other compound among 54 arylsulfonamides tested with detectable growth inhibition of M. smegmatis.
CiteXplore: 17258454
DOI: 10.1016/j.bmcl.2006.11.079
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets