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ID: ALA1139391
Journal: Bioorg Med Chem Lett
Title: Synthesis and structure-activity relationship of benzetimide derivatives as human CXCR3 antagonists.
Authors: Bongartz JP, Buntinx M, Coesemans E, Hermans B, Lommen GV, Wauwe JV.
Abstract: The synthesis and evaluation of benzetimide derivatives showing potent CXCR3 antagonism are described. Optimization of the screening hits led to the identification of more potent CXCR3 antagonists devoid of anti-cholinergic activity and identification of the key pharmacophore moieties of the series.
CiteXplore: 18922694