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ID: ALA1139407
Journal: Bioorg Med Chem Lett
Title: Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer.
Authors: Scott DA, Aquila BM, Bebernitz GA, Cook DJ, Dakin LA, Deegan TL, Hattersley MM, Ioannidis S, Lyne PD, Omer CA, Ye M, Zheng X.
Abstract: The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.
CiteXplore: 18694641