Pestalachlorides A-C, antifungal metabolites from the plant endophytic fungus Pestalotiopsis adusta.
Basic Information
ID: ALA1139409
Journal: Bioorg Med Chem
Title: Pestalachlorides A-C, antifungal metabolites from the plant endophytic fungus Pestalotiopsis adusta.
Authors: Li E, Jiang L, Guo L, Zhang H, Che Y.
Abstract: Pestalachlorides A-C (1-3), three new chlorinated benzophenone derivatives, have been isolated from cultures of an isolate of the plant endophytic fungus Pestalotiopsis adusta. The structures of these compounds were determined mainly by NMR spectroscopy, and the structures of 1 and 3 were further confirmed by X-ray crystallography. Pestalachloride A (1) was obtained as a mixture of two inseparable atropisomers (1a and 1b), whereas pestalachloride C (3) was found to be a racemic mixture. Compounds 1 and 2 displayed significant antifungal activities against three plant pathogens.
CiteXplore: 18694644
DOI: 10.1016/j.bmc.2008.07.075
Patent ID: ┄