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ID: ALA1139695

Journal: Bioorg Med Chem Lett

Title: Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3.

Authors: Chen JJ, Thakur KD, Clark MP, Laughlin SK, George KM, Bookland RG, Davis JR, Cabrera EJ, Easwaran V, De B, George Zhang Y.

Abstract: A new class of pyrimidine-based Janus tyrosine kinase 3 (JAK3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK3.

CiteXplore: 16934457

DOI: 10.1016/j.bmcl.2006.08.022