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ID: ALA1140547

Journal: Bioorg Med Chem Lett

Title: Potent oxindole based human beta3 adrenergic receptor agonists.

Authors: Stevens FC, Bloomquist WE, Borel AG, Cohen ML, Droste CA, Heiman ML, Kriauciunas A, Sall DJ, Tinsley FC, Jesudason CD.

Abstract: The synthesis and biological evaluation of a series of oxindole beta(3) adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety.

CiteXplore: 17911024

DOI: 10.1016/j.bmcl.2007.09.011