New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

ID: ALA1140550

Journal: Bioorg Med Chem Lett

Title: New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

Authors: Frohn M, Xu H, Zou X, Chang C, McElvaine M, Plant MH, Wong M, Tagari P, Hungate R, Bürli RW.

Abstract: We report the development of the novel N-substituted benzimidazole 11 as a potent and selective human formyl peptide receptor-like 1 (hFPRL1) agonist. This compound and its less active enantiomer 12 were identified as useful tools for studying receptor function in vitro.

CiteXplore: 17920884

DOI: 10.1016/j.bmcl.2007.09.043

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