Basic Information
ID: ALA1140612
Journal: Eur J Med Chem
Title: 4-Methyl-1,2,3-selenadiazole-5-carboxylic acid amides: antitumor action and cytotoxic effect correlation.
Authors: Arsenyan P, Rubina K, Shestakova I, Domracheva I.
Abstract: Synthesis and cytotoxic activity of a series of 4-methyl-1,2,3-selenadiazole-5-carboxylic acid amides on human fibrosarcoma HT-1080, mouse hepatoma MG-22A, and mouse fibroblasts 3T3 cell lines are described. The correlation between compound LD(50) and 3T3 fibroblast cell line morphology was shown. In vivo evaluation of amides on mouse sarcoma S-180 confirms high antitumor activity (58-85%).
CiteXplore: 17275964
DOI: 10.1016/j.ejmech.2006.12.004
Patent ID: ┄
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