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ID: ALA1140832

Journal: Bioorg Med Chem Lett

Title: Antimitotic quinoid triterpenes from Maytenus chuchuhuasca.

Authors: Morita H, Hirasawa Y, Muto A, Yoshida T, Sekita S, Shirota O.

Abstract: Four cytotoxic quinoid triterpenes, tingenone (1), 22 beta-hydroxytingenone (2), pristimerin (3), and celastrol (4), isolated from Maytenus chuchuhuasca, potently inhibit the polymerization of tubulin.

CiteXplore: 18164197

DOI: 10.1016/j.bmcl.2007.12.016