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ID: ALA1141060
Journal: Bioorg Med Chem Lett
Title: A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
Authors: Rizzi E, Dallavalle S, Merlini L, Beretta GL, Pratesi G, Zunino F.
Abstract: A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic esters of 2-iodophenols, is reported. The cytotoxic activity of these isoaurones is lower than that of the structurally very similar 4-arylcoumarins.
CiteXplore: 16040242