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ID: ALA1141202
Journal: Bioorg Med Chem Lett
Title: Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.
Authors: Revesz L, Bollbuck B, Buhl T, Eder J, Esser R, Feifel R, Heng R, Hiestand P, Jachez-Demange B, Loetscher P, Sparrer H, Schlapbach A, Waelchli R.
Abstract: Cinnamides as novel CCR1 antagonist chemotypes are described with high affinity to human and rodent receptors. A1B1 and A4B7 showed oral activity in the mouse collagen induced arthritis.
CiteXplore: 16198561