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ID: ALA1141242
Journal: Bioorg Med Chem Lett
Title: Estrogen receptor beta selective ligands: discovery and SAR of novel heterocyclic ligands.
Authors: Chesworth R, Wessel MD, Heyden L, Mangano FM, Zawistoski M, Gegnas L, Galluzzo D, Lefker B, Cameron KO, Tickner J, Lu B, Castleberry TA, Petersen DN, Brault A, Perry P, Ng O, Owen TA, Pan L, Ke HZ, Brown TA, Thompson DD, DaSilva-Jardine P.
Abstract: A series of ligands with varying heterocyclic cores and substituents that display a range of selectivity's (up to >100x) for ER-beta over ER-alpha are reported.
CiteXplore: 16219463