Document Report Card

ID: ALA1141442

Journal: J Nat Prod

Title: Structure elucidation of a dihydropyranone from Tapinanthus dodoneifolius.

Authors: Ouedraogo M, Carreyre H, Vandebrouck C, Bescond J, Raymond G, Guissou IP, Cognard C, Becq F, Potreau D, Cousson A, Marrot J, Coustard JM.

Abstract: A new dihydropyranone, ( R)-6-[( S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6-dihydropyran-2-one ( 1), was isolated from Tapinanthus dodoneifolius. The structure was determined from spectroscopic and X-ray crystallographic analysis. Compound 1 (named dodoneine) showed a relaxing effect on preconstricted rat aortic rings (IC 50 of 81.4 +/- 0.9 microM).

CiteXplore: 18052322

DOI: 10.1021/np070355x