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ID: ALA1141626
Journal: Bioorg Med Chem Lett
Title: Thiosemicarbazones active against Clostridium difficile.
Authors: Costello C, Karpanen T, Lambert PA, Mistry P, Parker KJ, Rathbone DL, Ren J, Wheeldon L, Worthington T.
Abstract: A set of closely related furylidene thiosemicarbazones was prepared and screened against various clinically important Gram-positive bacteria. One compound containing an ethylene spacer and a 5-nitrofuryl group was found to have promising activity against Clostridium difficile.
CiteXplore: 18243694