Document Report Card

ID: ALA1141835

Journal: J Nat Prod

Title: Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of penicillium sclerotigenum

Authors: Joshi BK, Gloer JB, Wicklow DT, Dowd PF.

Abstract: A new benzodiazepine, sclerotigenin (1), was isolated from organic extracts of the sclerotia of Penicillium sclerotigenum (NRRL 3461) along with two known griseofulvin analogues. The structure of 1 was determined primarily by analysis of 1H NMR, 13C NMR, HMQC, and HMBC data. Compound 1 was the major component of the CH2Cl2 extract of P. sclerotigenum sclerotia and is responsible for most of the antiinsectan activity of the extract against the crop pest Helicoverpa zea.

CiteXplore: 10217735

DOI: 10.1021/np980511n