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ID: ALA1141862
Journal: Bioorg Med Chem Lett
Title: Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases.
Authors: Pan W, Liu H, Xu YJ, Chen X, Kim KH, Milligan DL, Columbus J, Hadari YR, Kussie P, Wong WC, Labelle M.
Abstract: Pyrimido-oxazepine based sub-micromolar inhibitors (2-4) for Aurora and FLT-3 were designed and synthesized. These preliminary results supported the potential use of pyrimido-oxazepines as a versatile template for developing specific kinase inhibitors.
CiteXplore: 16198560