Novel beta-(imidazol-4-yl)-beta-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase t...
Basic Information
ID: ALA1141912
Journal: Bioorg Med Chem Lett
Title: Novel beta-(imidazol-4-yl)-beta-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I.
Authors: Saha AK, End DW.
Abstract: Solid-phase synthesis of imidazolyl-beta-amino acid derivatives is described. Several analogs demonstrated moderate inhibition of geranylgeranyl protein transferase type I (GGPT I).
CiteXplore: 15745827
DOI: 10.1016/j.bmcl.2005.01.042
Patent ID: ┄
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