Document Report Card

ID: ALA1142180

Journal: Antimicrob Agents Chemother

Title: First characterization of fluoroquinolone resistance in Streptococcus suis.

Authors: Escudero JA, San Millan A, Catalan A, de la Campa AG, Rivero E, Lopez G, Dominguez L, Moreno MA, Gonzalez-Zorn B.

Abstract: We have identified and sequenced the genes encoding the quinolone-resistance determining region (QRDR) of ParC and GyrA in fluoroquinolone-susceptible and -resistant Streptococcus suis clinical isolates. Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria.

CiteXplore: 17116660

DOI: 10.1128/aac.00972-06