Document Report Card
Basic Information
ID: ALA1142269
Journal: Bioorg Med Chem Lett
Title: Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway.
Authors: Stauffer F, Maira SM, Furet P, García-Echeverría C.
Abstract: Imidazo[4,5-c]quinoline derivatives have been discovered and developed as potent and effective modulators of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) pathway to lead to clinical development candidates. The SAR data of representative examples of this compound class and their biological profiling in cellular and in vivo settings are presented and discussed.
CiteXplore: 18248814