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ID: ALA1142384
Journal: Bioorg Med Chem
Title: Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity.
Authors: Sako K, Aoyama H, Sato S, Hashimoto Y, Baba M.
Abstract: Based on anti-viral screening of our heteroaromatics derived from thalidomide, the gamma-carboline skeleton has been identified as a superior scaffold structure for compounds with potent anti-bovine viral diarrhea virus (BVDV) activity. Structural development studies led to a potent anti-viral agent, SK5M (5-methyl-gamma-carboline), with the EC(50) of 0.26 microM.
CiteXplore: 18289862