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ID: ALA1142476
Journal: Bioorg Med Chem Lett
Title: Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp.
Authors: Lee D, Shin J, Yoon KM, Kim TI, Lee SH, Lee HS, Oh KB.
Abstract: Seven sesterterpene sulfates (1-7) were isolated from the tropical sponge Dysidea sp. and their inhibitory activities against isocitrate lyase (ICL) from Candida albicans were evaluated. Among the isolated natural products compound 6 and 7 were found to be strong ICL inhibitors. The isolated compounds (1-7) also showed potent antibacterial effect against Bacillus subtilis and Proteus vulgaris, but did not display antifungal activity.
CiteXplore: 18824352