Document Report Card

ID: ALA1142639

Journal: J Nat Prod

Title: New triterpenoid saponins from the sponge Melophlus isis.

Authors: Lee HS, Seo Y, Cho KW, Rho JR, Shin J, Paul VJ.

Abstract: Four new triterpenoid saponins were isolated, along with two known 30-norlanostane-type saponins- sarasinosides A(1) (1) and A(3) (2)-from the sponge Melophlus isis collected from Guam. The structures of these new compounds (3-6) proved to be 30-norlanosta-8(14),24-dien-23-ones bearing two hydroxyl groups or the corresponding methoxy groups at the 9alpha,15alpha- and 9alpha, 15beta-positions and the pentasaccharide portion identical with those of 1 and 2 at the 3beta position, by spectral, chemical, and GC analyses.

CiteXplore: 10924165

DOI: 10.1021/np990589j