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ID: ALA1142785
Journal: Bioorg Med Chem Lett
Title: Synthesis of novel curcumin mimics with asymmetrical units and their anti-angiogenic activity.
Authors: Woo HB, Shin WS, Lee S, Ahn CM.
Abstract: Novel curcumin mimics with asymmetrical units phenyl group with alkyl amide, chloro-substituted benzamide, or heteroaromatic amide moieties were synthesized and their anti-angiogenic activity was evaluated with the proliferation and tube formation inhibitory activity on the human umbilical vein endothelial cells. Compounds 5, 14, 17, and 18 showed potent growth inhibitory activity and tube formation inhibitory activity.
CiteXplore: 15993583