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ID: ALA1142791
Journal: Bioorg Med Chem Lett
Title: Design, synthesis, and evaluation of 2-phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors.
Authors: Sheng R, Lin X, Li J, Jiang Y, Shang Z, Hu Y.
Abstract: A series of 2-phenoxy-indan-1-one derivatives have been designed, synthesized, and tested as acetylcholinesterase inhibitors. The most potent compound exhibited high AChE inhibitory activity (IC50 = 50 nM), and the molecular docking study indicated that it was nicely accommodated by AChE.
CiteXplore: 15993600