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ID: ALA1142803
Journal: Bioorg Med Chem Lett
Title: Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents.
Authors: Suresh Babu K, Hari Babu T, Srinivas PV, Sastry BS, Hara Kishore K, Murty US, Madhusudana Rao J.
Abstract: A series of Oroxylin A derivatives, prepared by alkylation and condensation, were fully characterized by spectroscopic methods. All the derivatives were screened for antibacterial activity against a panel of susceptible and resistant Gram-positive and Gram-negative organisms. It was observed that acylation of 7-OH group in Oroxylin A significantly enhanced the activity as compared to their parent compound (Oroxylin A).
CiteXplore: 16046127