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ID: ALA1143094

Journal: Bioorg Med Chem Lett

Title: IRAK-4 inhibitors. Part 1: a series of amides.

Authors: Buckley GM, Gowers L, Higueruelo AP, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD, Sabin V, Fraser JL.

Abstract: The synthesis and profile of a series of amides are described. Some of these compounds were potent IRAK-4 inhibitors and two examples were evaluated in vivo.

CiteXplore: 18474425

DOI: 10.1016/j.bmcl.2008.04.058