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ID: ALA1143158
Journal: Bioorg Med Chem Lett
Title: Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization.
Authors: Colabufo NA, Abate C, Contino M, Inglese C, Ferorelli S, Berardi F, Perrone R.
Abstract: A potent sigma-2 receptor ligand, known as PB28, was tritium radiolabelled and biologically evaluated. The results showed that [(3)H]PB28 and the corresponding unlabelled PB28 had superimposed pharmacodynamic properties. This radioligand appears as a potential candidate for receptor binding and in living cells assays.
CiteXplore: 18178434