Document Report Card
Basic Information
ID: ALA1143226
Journal: J Med Chem
Title: Potent inhibitors of the hedgehog signaling pathway.
Authors: Brunton SA, Stibbard JH, Rubin LL, Kruse LI, Guicherit OM, Boyd EA, Price S.
Abstract: A small family of phenyl quinazolinone ureas is reported as potent modulators of Hedgehog protein function. Preliminary SAR studies of the urea substituent led to a nanomolar Hedgehog antagonist.
CiteXplore: 18275133
DOI: 10.1021/jm070694n