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ID: ALA1143229
Journal: Bioorg Med Chem Lett
Title: PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma.
Authors: Colabufo NA, Abate C, Contino M, Inglese C, Niso M, Berardi F, Perrone R.
Abstract: PB183, a non-selective sigma receptor ligand displaying high sigma-1 and sigma-2 receptor affinity, was evaluated in prostate tumour cell lines for its suitability as PET radiotracer. The pharmacodynamic and pharmacokinetic properties suggested PB183 as a potential PET radiotracer to visualize prostate adenocarcinoma.
CiteXplore: 18276137