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ID: ALA1143265
Journal: Bioorg Med Chem Lett
Title: Discovery of thiophene inhibitors of polo-like kinase.
Authors: Emmitte KA, Andrews CW, Badiang JG, Davis-Ward RG, Dickson HD, Drewry DH, Emerson HK, Epperly AH, Hassler DF, Knick VB, Kuntz KW, Lansing TJ, Linn JA, Mook RA, Nailor KE, Salovich JM, Spehar GM, Cheung M.
Abstract: The discovery and development of a series of thiophenes as potent and selective inhibitors of PLK is described. Identification and characterization of 2, a useful in vitro PLK inhibitor tool compound, is also presented.
CiteXplore: 19097784