Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.

Basic Information

ID: ALA1143410

Journal: Antimicrob Agents Chemother

Title: Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.

Authors: Swarup V, Ghosh J, Ghosh S, Saxena A, Basu A.

Abstract: Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

CiteXplore: 17576830

DOI: 10.1128/aac.00041-07

Patent ID: