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Basic Information

ID: ALA1143482

Journal: Bioorg Med Chem Lett

Title: Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators.

Authors: Lahm GP, Selby TP, Freudenberger JH, Stevenson TM, Myers BJ, Seburyamo G, Smith BK, Flexner L, Clark CE, Cordova D.

Abstract: A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented.

CiteXplore: 16165355

DOI: 10.1016/j.bmcl.2005.08.034