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ID: ALA1143905
Journal: Bioorg Med Chem Lett
Title: Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors.
Authors: Haldar MK, Scott MD, Sule N, Srivastava DK, Mallik S.
Abstract: The syntheses of a new class of barbiturate-based inhibitors for human and Escherichia Coli methionine aminopeptidase-1 (MetAP-1) are described. Some of the synthesized inhibitors show selective inhibition of the human enzyme with high potency.
CiteXplore: 18343108