Document Report Card

ID: ALA1144097

Journal: J Nat Prod

Title: Triterpene trimers from Maytenus scutioides: cycloaddition compounds?

Authors: González AG, Alvarenga NL, Bazzocchi IL, Ravelo AG, Moujir L.

Abstract: Two novel trimers, triscutins A and B (1 and 2), based on pristimerin triterpene units, were isolated and characterized from Maytenus scutioides. Their structures were determined on the basis of spectroscopic evidence, including 1H-13C heteronuclear correlation (HMQC), long-range correlation with inverse detection (HMBC), and ROESY NMR experiments; and their absolute configurations, by means of CD studies. Compounds 1 and 2 were assayed for antimicrobial and cytotoxic activities, and their possible biosynthetic route is proposed.

CiteXplore: 10479335

DOI: 10.1021/np9900728