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ID: ALA1144368

Journal: Bioorg Med Chem Lett

Title: Synthesis of 15R-PGD2: a potential DP2 receptor agonist.

Authors: Kim S, Bellone S, Maxey KM, Powell WS, Lee GJ, Rokach J.

Abstract: The first total synthesis of 15R-PGD(2)3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE(2). 15R-PGD(2), a potential DP(2) receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases.

CiteXplore: 15780624

DOI: 10.1016/j.bmcl.2005.02.011