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ID: ALA1144391

Journal: Bioorg Med Chem Lett

Title: New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors.

Authors: Feixas J, Giovannoni MP, Vergelli C, Gavaldà A, Cesari N, Graziano A, Dal Piaz V.

Abstract: A series of potent PDE5 inhibitors with high selectivity versus PDE6 isoenzymes was identified.

CiteXplore: 15837329

DOI: 10.1016/j.bmcl.2005.02.090