Document Report Card
Basic Information
ID: ALA1144794
Journal: Bioorg Med Chem Lett
Title: Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
Authors: Ando T, Kojima K, Chahota P, Kozaki A, Milind ND, Kitade Y.
Abstract: 4'-Modified noraristeromycin (NAM) analogs, 4'-sulfo-, 4'-sulfamoy, 4'-azido and 4'-amino-NAM, were systematically synthesized. The inhibitory activities of these analogs and related compounds against Plasmodium falciparum and human S-adenosyl-L-homocysteine hydrolase were investigated.
CiteXplore: 18374570