Basic Information
ID: ALA1144972
Journal: Bioorg Med Chem Lett
Title: Benzo[f]naphtyridones: a new family of topical antibacterial agents active on multi-resistant Gram-positive pathogens.
Authors: Tabart M, Picaut G, Lavergne M, Wentzler S, Malleron JL, Dutka-Malen S, Berthaud N.
Abstract: The synthesis and antibacterial activity of benzo[f][1,7]naphtyridone derivatives are reported. These compounds are potent antibacterial agents with a Gram-positive spectrum of activity. They are active against multi-resistant cocci, especially Staphylococcus aureus strains. Their physico-chemical and biological properties make them particularly suitable for topical antibacterial use.
CiteXplore: 12657275
DOI: 10.1016/s0960-894x(03)00057-x
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets