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ID: ALA1144977
Journal: Bioorg Med Chem Lett
Title: Synthesis of pyrimidinopyridine-triazene conjugates targeted to abl tyrosine kinase.
Authors: Rachid Z, Katsoulas A, Brahimi F, Jean-Claude BJ.
Abstract: The synthesis and abl tyrosine kinase inhibitory activities of alkyltriazenes conjugated to phenylaminopyrimidines are described. Significant abl inhibitory activities were observed only when a benzamido spacer was inserted between the 1,2,3-triazene chain and the 2-phenyaminopyridopyrimidine moiety.
CiteXplore: 12951113