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ID: ALA1144986
Journal: Bioorg Med Chem Lett
Title: Binding of beta-carbolines at 5-HT(2) serotonin receptors.
Authors: Grella B, Teitler M, Smith C, Herrick-Davis K, Glennon RA.
Abstract: A series of ring-substituted (i.e., methoxy and bromo) 3,4-dihydro- and 1,2,3,4-tetrahydro-beta-carbolines was examined at 5-HT(2A) and 5-HT(2C) serotonin receptors. Whereas most of the methoxy-substituted derivatives typically displayed affinities similar to their unsubstituted parents, certain (particularly 8-substituted) bromo derivatives displayed enhanced affinity. A binding profile was obtained for selected beta-carbolines.
CiteXplore: 14643338