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ID: ALA1145227

Journal: Bioorg Med Chem Lett

Title: 5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa.

Authors: Qiao JX, Cheng X, Modi DP, Rossi KA, Luettgen JM, Knabb RM, Jadhav PK, Wexler RR.

Abstract: Syntheses and SAR studies of 5-amidinobenzo[b]thiophene analogs provided compounds with low submicromolar factor IXa activity and equal or slightly better selectivity relative to factor Xa.

CiteXplore: 15582405

DOI: 10.1016/j.bmcl.2004.10.045